Scleroderma present with acute gastritis: A rare case report

Systemic sclerosis (SSc) is a systemic autoimmune disease in which gastrointestinal manifestations are a frequent complication. In as many as 90% of cases, there is intestinal involvement. The oesophagus and the anorectal tract are the regions most impacted. Digestion-related discomfort is most commonly caused by reflux, heartburn, and dysmotility. The development of faecal incontinence is significantly influenced by disordered anorectal function, which can happen early in the course of SSc. Oesophageal dysmotility, heartburn, dysphagia, nausea, vomiting, diarrhoea, constipation, bloating/distension, and faecal incontinence are among the symptoms of scleroderma that are frequently experienced. An endoscopy examination and manometry measurements are used to diagnose systemic sclerosis. Proton pump inhibitors, h2 receptor blockers, prokinetics, antibiotics, and laxatives are currently advised for the treatment of gastrointestinal disorders in SSc patients.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-10-31
DOI
https://doi.org/10.5281/zenodo.17589510
Primary Topic
Systemic Sclerosis and Related Diseases
Type
article
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article

Scleroderma present with acute gastritis: A rare case report

Zenodo (CERN European Organization for Nuclear Research)
Systemic Sclerosis and Related Diseases
article

Scleroderma present with acute gastritis: A rare case report

article en

Abstract

Systemic sclerosis (SSc) is a systemic autoimmune disease in which gastrointestinal manifestations are a frequent complication. In as many as 90% of cases, there is intestinal involvement. The oesophagus and the anorectal tract are the regions most impacted. Digestion-related discomfort is most commonly caused by reflux, heartburn, and dysmotility. The development of faecal incontinence is significantly influenced by disordered anorectal function, which can happen early in the course of SSc. Oesophageal dysmotility, heartburn, dysphagia, nausea, vomiting, diarrhoea, constipation, bloating/distension, and faecal incontinence are among the symptoms of scleroderma that are frequently experienced. An endoscopy examination and manometry measurements are used to diagnose systemic sclerosis. Proton pump inhibitors, h2 receptor blockers, prokinetics, antibiotics, and laxatives are currently advised for the treatment of gastrointestinal disorders in SSc patients.

Zenodo (CERN European Organization for Nuclear Research)
Defence Research and Development Laboratory (IN)
Good health and well-being
Openalex Percentile: Top 35%
Systemic Sclerosis and Related Diseases
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Scleroderma present with acute gastritis: A rare case report · Zenodo (CERN European Organization for Nuclear Research) (2025) | TGRS Research Map | TGRS