Effect of Aerobic Exercise on Chronic Tension-Type Headache

This document describes the study protocol approved by the Ethics Committee of Aragón (CEICA, Spain; reference PI22/197, Acta Nº 10/2022) and amended in November 2025 to align with the Doctoral Thesis in Health and Sport Sciences at the University of Zaragoza. The study aims to evaluate the effects of a supervised aerobic exercise program on pain intensity, disability, and central sensitization in adults with chronic tension-type headache through a prospective quasi-experimental single-group design. The document includes the methodology, timeline, participant information sheet, and ethical approval details. It ensures transparency, reproducibility, and compliance with European data protection regulations (GDPR 2016/679 and Organic Law 3/2018). Funding: Self-funded doctoral project, University of Zaragoza. Ethical Approval: CEICA PI22/197, Acta Nº 10/2022. Principal Investigator: Cindy Johana Palacio-Del Río. Supervisors: Dra. María Orosia Lucha-López, Dr. José Miguel Tricás-Moreno.