Weight-based Levothyroxine Dose Calculator for Hypothyroidism in Adults
This weight-based levothyroxine dose calculator provides an evidence-based tool to estimate initial thyroid hormone replacement needs in adults with primary hypothyroidism and minimal residual thyroid function. The formula uses a standard starting dose of 1.6 mcg/kg/day, with adjustments for special populations such as those with obesity, advanced age, or cardiac disease. The calculator is intended for non-pregnant adults under 65 years without ischemic heart disease and serves as a practical aid to guide starting therapy, recognizing the importance of ongoing monitoring, individualized titration, and clinical judgment in optimizing patient outcomes.
Institutions
- Cleveland Clinic (US)
Publication Details
- Journal
- Evidence to Action Official Journal of MDCalc
- Published
- 2025-10-28
- DOI
- https://doi.org/10.65357/001c.145848
- Primary Topic
- Thyroid Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00