First Reported Case of Oral Ulceration Induced by Improper Sodium Ibandronate Administration in a Geriatric Patient

The prevalence of osteoporosis is increasing, and bisphosphonate (BP) medications are widely used for its treatment. Oral BP drugs carry the risk of esophageal ulcers, which can be mitigated by following the proper administration guidelines. However, cases of oral ulceration caused by misuse, such as chewing of tablets predominantly comprising alendronate sodium, have been reported globally. Herein, we report the first case of oral ulceration attributed to the misuse of sodium ibandronate.

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Publication Details

Journal
Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences)
Published
2025-11-09
DOI
https://doi.org/10.5649/jjphcs.51.734
Primary Topic
Bone health and treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

First Reported Case of Oral Ulceration Induced by Improper Sodium Ibandronate Administration in a Geriatric Patient

Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences)
Bone health and treatments
article

First Reported Case of Oral Ulceration Induced by Improper Sodium Ibandronate Administration in a Geriatric Patient

article en

Abstract

The prevalence of osteoporosis is increasing, and bisphosphonate (BP) medications are widely used for its treatment. Oral BP drugs carry the risk of esophageal ulcers, which can be mitigated by following the proper administration guidelines. However, cases of oral ulceration caused by misuse, such as chewing of tablets predominantly comprising alendronate sodium, have been reported globally. Herein, we report the first case of oral ulceration attributed to the misuse of sodium ibandronate.

Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences)Vol. 51(11)
Osaki Citizen Hospital (JP)
Good health and well-being
Openalex Percentile: Top 36%
Bone health and treatments
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First Reported Case of Oral Ulceration Induced by Improper Sodium Ibandronate Administration in a Geriatric Patient · Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences) (2025) | TGRS Research Map | TGRS