Assessment Of Entada Spiralis Root Extract Toxicity Using Zebrafish Embryo Model

This research investigates the acute toxicity of Entada spiralis root extract using zebrafish embryo assay. Observations were made on hatching success, coagulation rate, and tail morphology. Toxicity onset occurred beyond 50 µg/mL, suggesting potential embryotoxic compounds. The study provides insight into safe dosage ranges for traditional medicine formulations. Examines acute toxicity endpoints in zebrafish embryos exposed to E. spiralis extract, offering data for dosage safety and toxicity benchmarking in herbal product development.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-11-08
DOI
https://doi.org/10.5281/zenodo.17557951
Primary Topic
Zebrafish Biomedical Research Applications
Type
article
Field-Weighted Citation Impact
0.00
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article

Assessment Of Entada Spiralis Root Extract Toxicity Using Zebrafish Embryo Model

Zenodo (CERN European Organization for Nuclear Research)
Zebrafish Biomedical Research Applications
article

Assessment Of Entada Spiralis Root Extract Toxicity Using Zebrafish Embryo Model

article en

Abstract

This research investigates the acute toxicity of Entada spiralis root extract using zebrafish embryo assay. Observations were made on hatching success, coagulation rate, and tail morphology. Toxicity onset occurred beyond 50 µg/mL, suggesting potential embryotoxic compounds. The study provides insight into safe dosage ranges for traditional medicine formulations. Examines acute toxicity endpoints in zebrafish embryos exposed to E. spiralis extract, offering data for dosage safety and toxicity benchmarking in herbal product development.

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 40%
Zebrafish Biomedical Research Applications
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Assessment Of Entada Spiralis Root Extract Toxicity Using Zebrafish Embryo Model · Zenodo (CERN European Organization for Nuclear Research) (2025) | TGRS Research Map | TGRS