Exploring Phytosome Technology for Improved anti-inflammatory activity of Murrayakoenigii Extracts in Therapeutics

The phytosome complexes demonstrated enhanced physicochemical properties, including a stable colloidal system with favorable particle size and zeta potential values. The FTIR analysis confirmed the successful interaction between the phospholipids and bioactive compounds, supporting the formation of phytosome complexes. With a high encapsulation efficiency of 85%, the phytosome formulation exhibited potential for sustained release of bioactive compounds, enhancing their bioavailability. The anti-inflammatory activity of the phytosome complexes was confirmed through significant inhibition of protein denaturation and hemolysis, with the complexes showing 75% and 80% inhibition, respectively, at a concentration of 50 μg/mL. These results highlight the promising therapeutic potential of phytosome complexes in the treatment of inflammation-related conditions.