Commissioning of the South African Isotope Facility

The South African Isotope Facility (SAIF) is a radioisotope production facility based around a 70 MeV Cyclotron from IBA. SAIF was commissioned at the end of 2023 and commenced commercial isotope production in 2024. The facility is located in three vaults at iThemba LABS in Cape Town. The vault design, radiation modelling, and an overview of construction are presented. The designs and commissioning of the cyclotron, beam lines, wobbler magnet, dedicated target stations and target transport system are described and discussed, along with their current performance.