The Impacts of Folic Acid on Hematological Parameters in German Shepherd Dogs with Parvovirus-Induced Anemia

Canine parvovirus often causes anemia in dogs, presenting significant therapeutic challenges. This study evaluated the effectiveness of folic acid supplementation in improving hematological parameters in German Shepherd dogs with parvovirus-induced anemia. Forty German Shepherd dogs diagnosed with parvovirus-induced anemia were randomly assigned to two groups: the control group received standard treatment alone, and the experimental group was administered 5 mg of folic acid daily in addition to standard treatment for two weeks. Significant improvements were observed in hematocrit, hemoglobin, mean corpuscular volume, and mean corpuscular hemoglobin concentration in the experimental group (p<0.05). No significant differences were observed in mean corpuscular hemoglobin, white blood cell count, and thrombocyte count between the groups. Folic acid supplementation improved several hematological parameters in dogs with parvovirus-induced anemia, highlighting its potential as an adjunctive therapeutic approach.

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Publication Details

Journal
SHILAP Revista de lepidopterología
Published
2025-06-01
DOI
https://doi.org/10.22103/vcbr.2025.24710.1042
Primary Topic
Folate and B Vitamins Research
Type
article
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article

The Impacts of Folic Acid on Hematological Parameters in German Shepherd Dogs with Parvovirus-Induced Anemia

SHILAP Revista de lepidopterología
Folate and B Vitamins Research
article

The Impacts of Folic Acid on Hematological Parameters in German Shepherd Dogs with Parvovirus-Induced Anemia

article en

Abstract

Canine parvovirus often causes anemia in dogs, presenting significant therapeutic challenges. This study evaluated the effectiveness of folic acid supplementation in improving hematological parameters in German Shepherd dogs with parvovirus-induced anemia. Forty German Shepherd dogs diagnosed with parvovirus-induced anemia were randomly assigned to two groups: the control group received standard treatment alone, and the experimental group was administered 5 mg of folic acid daily in addition to standard treatment for two weeks. Significant improvements were observed in hematocrit, hemoglobin, mean corpuscular volume, and mean corpuscular hemoglobin concentration in the experimental group (p<0.05). No significant differences were observed in mean corpuscular hemoglobin, white blood cell count, and thrombocyte count between the groups. Folic acid supplementation improved several hematological parameters in dogs with parvovirus-induced anemia, highlighting its potential as an adjunctive therapeutic approach.

SHILAP Revista de lepidopterología
Islamic Azad University, Tehran (IR)
Good health and well-being
Openalex Percentile: Top 34%
Folate and B Vitamins Research
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The Impacts of Folic Acid on Hematological Parameters in German Shepherd Dogs with Parvovirus-Induced Anemia · SHILAP Revista de lepidopterología (2025) | TGRS Research Map | TGRS