Metal-free stereoselective C(sp <sup>3</sup> )–H indolation of N-heterocycles to potent antimicrobial non-canonical tryp–pro hybrids

Direct diastereoselective C–H indolations of N-heterocycles under metal and oxidant-free conditions have been developed for one-step access to enantioenriched indolyl N-heterocycles as new antibacterial scaffolds against multidrug-resistant strains.

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Publication Details

Journal
Green Chemistry
Published
2025-11-04
DOI
https://doi.org/10.1039/d5gc04622j
Primary Topic
Catalytic C–H Functionalization Methods
Type
article
Field-Weighted Citation Impact
0.00
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article

Metal-free stereoselective C(sp 3 )–H indolation of N-heterocycles to potent antimicrobial non-canonical tryp–pro hybrids

Green Chemistry
Catalytic C–H Functionalization Methods
article

Metal-free stereoselective C(sp 3 )–H indolation of N-heterocycles to potent antimicrobial non-canonical tryp–pro hybrids

article en

Abstract

Direct diastereoselective C–H indolations of N-heterocycles under metal and oxidant-free conditions have been developed for one-step access to enantioenriched indolyl N-heterocycles as new antibacterial scaffolds against multidrug-resistant strains.

Green ChemistryVol. 28(1)
Indian Institute of Technology Guwahati (IN), Central Drug Research Institute (IN), Academy of Scientific and Innovative Research (IN)
Openalex Percentile: Top 44%
Catalytic C–H Functionalization Methods
DOISourceOpenAlex
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Metal-free stereoselective C(sp <sup>3</sup> )–H indolation of N-heterocycles to potent antimicrobial non-canonical tryp–pro hybrids · Green Chemistry (2025) | TGRS Research Map | TGRS