Efficient Heritability Estimation in Multivariate Generalized Linear Models via Low-Rank Approximations

Introduction: Linear mixed models are widely used in genetics to estimate genetic variance components from SNP data. These models typically assume that phenotypes follow a (multivariate) normal distribution. However, in many practical settings, phenotype distributions deviate from normality, limiting [for full text, please go to the a.m. URL]

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Publication Details

Journal
German Medical Science (German Research Foundation)
Published
2025-11-03
DOI
https://doi.org/10.3205/25gmds005
Primary Topic
Genetic and phenotypic traits in livestock
Type
article
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article

Efficient Heritability Estimation in Multivariate Generalized Linear Models via Low-Rank Approximations

German Medical Science (German Research Foundation)
Genetic and phenotypic traits in livestock
article

Efficient Heritability Estimation in Multivariate Generalized Linear Models via Low-Rank Approximations

article en

Abstract

Introduction: Linear mixed models are widely used in genetics to estimate genetic variance components from SNP data. These models typically assume that phenotypes follow a (multivariate) normal distribution. However, in many practical settings, phenotype distributions deviate from normality, limiting [for full text, please go to the a.m. URL]

German Medical Science (German Research Foundation)
University of Southern Denmark (DK), Universidade Federal do Paraná (BR), Technische Universität Braunschweig (DE)
Openalex Percentile: Top 32%
Genetic and phenotypic traits in livestock
DOIOpen Access PDFOpenAlex
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