Combining machine learning methods for subgroup identification in time-to-event data with approximate Bayesian computation for bias correction

Personalized medicine is a crucial aspect in finding effective treatments for patients. In clinical development it is essential to identify subgroups of patients who exhibit a beneficial treatment effect, ideally before moving to confirmatory trials. The identified subgroups could be defined by predictive [for full text, please go to the a.m. URL]

Institutions

Publication Details

Journal
German Medical Science (German Research Foundation)
Published
2025-11-03
DOI
https://doi.org/10.3205/25gmds067
Primary Topic
Statistical Methods in Clinical Trials
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Combining machine learning methods for subgroup identification in time-to-event data with approximate Bayesian computation for bias correction

German Medical Science (German Research Foundation)
Statistical Methods in Clinical Trials
article

Combining machine learning methods for subgroup identification in time-to-event data with approximate Bayesian computation for bias correction

article en

Abstract

Personalized medicine is a crucial aspect in finding effective treatments for patients. In clinical development it is essential to identify subgroups of patients who exhibit a beneficial treatment effect, ideally before moving to confirmatory trials. The identified subgroups could be defined by predictive [for full text, please go to the a.m. URL]

German Medical Science (German Research Foundation)
Darmstadt University of Applied Sciences (DE), Merck KGaA, Darmstadt (Germany) (DE)
Quality Education
Openalex Percentile: Top 36%
Statistical Methods in Clinical Trials
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.