Combining machine learning methods for subgroup identification in time-to-event data with approximate Bayesian computation for bias correction
Personalized medicine is a crucial aspect in finding effective treatments for patients. In clinical development it is essential to identify subgroups of patients who exhibit a beneficial treatment effect, ideally before moving to confirmatory trials. The identified subgroups could be defined by predictive [for full text, please go to the a.m. URL]
Institutions
- Darmstadt University of Applied Sciences (DE)
- Merck KGaA, Darmstadt (Germany) (DE)
Publication Details
- Journal
- German Medical Science (German Research Foundation)
- Published
- 2025-11-03
- DOI
- https://doi.org/10.3205/25gmds067
- Primary Topic
- Statistical Methods in Clinical Trials
- Type
- article
- Field-Weighted Citation Impact
- 0.00