An Open Labelled Prospective Cohort Study To Evaluate The Haemostatic Effect Of Polyherbal Nanogel In The Management Of Arshas (Hemorrhoids)

Arshas (Hemorrhoids) are the dilated veins within the anal canal formed by Superior, Inferior & Medial rectal veins because of downward sliding of the anal cushion due to straining. The disease is common among age group between 30-65 years with a prevalence rate of 4.4%. Treatment advancements like LHP, DGHAL, sclerotherapy & hemorrhoidopexy are less invasive & painless but has high reoccurrence rate. Being difficult to access the position of the colon, the drugs are targeted to the site by formulating the drug molecule in semi solid form with suitable polymers. The snigdha, tikshna & lekhana guna of Kasisadi Taila, helps in reducing size, pain & bleeding and Lajjalu (Mimosa pudica) being a raktstambhaka proves beneficial in Arshas (Hemorrhoids), when combined in a nanogel form helps in achieving safe & effective drug administration. The polyherbal nanogel was prepared by collecting the raw drug, drying, pulverising & converting it into nanogel. A group of 15 patients from Shalya Tantra OPD of Ayurveda College Coimbatore having 1st, 2nd & 3rd degree Arshas (Hemorrhoids) were selected for the study and the nanogel prepared out of Lajjalu (Mimosa pudica) & Kasisadi Taila was applied once daily for 7-15 days regularly in a dose of 200mg. The assessment on 21st day showed significant results in reducing bleeding, pile mass, pruritis & mucoid discharge, proving Polyherbal Nanogel is low-cost, non-invasive, safe & efficient for Arshas (Hemorrhoids).

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-08-30
DOI
https://doi.org/10.5281/zenodo.17512769
Primary Topic
Anorectal Disease Treatments and Outcomes
Type
article
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article

An Open Labelled Prospective Cohort Study To Evaluate The Haemostatic Effect Of Polyherbal Nanogel In The Management Of Arshas (Hemorrhoids)

Zenodo (CERN European Organization for Nuclear Research)
Anorectal Disease Treatments and Outcomes
article

An Open Labelled Prospective Cohort Study To Evaluate The Haemostatic Effect Of Polyherbal Nanogel In The Management Of Arshas (Hemorrhoids)

article en

Abstract

Arshas (Hemorrhoids) are the dilated veins within the anal canal formed by Superior, Inferior & Medial rectal veins because of downward sliding of the anal cushion due to straining. The disease is common among age group between 30-65 years with a prevalence rate of 4.4%. Treatment advancements like LHP, DGHAL, sclerotherapy & hemorrhoidopexy are less invasive & painless but has high reoccurrence rate. Being difficult to access the position of the colon, the drugs are targeted to the site by formulating the drug molecule in semi solid form with suitable polymers. The snigdha, tikshna & lekhana guna of Kasisadi Taila, helps in reducing size, pain & bleeding and Lajjalu (Mimosa pudica) being a raktstambhaka proves beneficial in Arshas (Hemorrhoids), when combined in a nanogel form helps in achieving safe & effective drug administration. The polyherbal nanogel was prepared by collecting the raw drug, drying, pulverising & converting it into nanogel. A group of 15 patients from Shalya Tantra OPD of Ayurveda College Coimbatore having 1st, 2nd & 3rd degree Arshas (Hemorrhoids) were selected for the study and the nanogel prepared out of Lajjalu (Mimosa pudica) & Kasisadi Taila was applied once daily for 7-15 days regularly in a dose of 200mg. The assessment on 21st day showed significant results in reducing bleeding, pile mass, pruritis & mucoid discharge, proving Polyherbal Nanogel is low-cost, non-invasive, safe & efficient for Arshas (Hemorrhoids).

Zenodo (CERN European Organization for Nuclear Research)
Vaidyaratnam P.S. Varier Ayurveda College (IN)
Good health and well-being
Openalex Percentile: Top 32%
Anorectal Disease Treatments and Outcomes
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