Metal concentrations in cerebrospinal fluid of patients with arthroplasty implants in situ – do CoCrMo components matter?

Objectives and questions: The NeuroWear pilot study demonstrated that Co, Ti, Nb and Zr released from arthroplasty implants may cross the blood-CNS barriers and significantly accumulate in cerebrospinal fluid (CSF). It found merely Co levels to be significantly correlated between blood and CSF. We aimed [for full text, please go to the a.m. URL]

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Publication Details

Journal
German Medical Science (German Research Foundation)
Published
2025-10-31
DOI
https://doi.org/10.3205/25dkou220
Primary Topic
Heavy Metal Exposure and Toxicity
Type
article
Field-Weighted Citation Impact
0.00
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article

Metal concentrations in cerebrospinal fluid of patients with arthroplasty implants in situ – do CoCrMo components matter?

German Medical Science (German Research Foundation)
Heavy Metal Exposure and Toxicity
article

Metal concentrations in cerebrospinal fluid of patients with arthroplasty implants in situ – do CoCrMo components matter?

article en

Abstract

Objectives and questions: The NeuroWear pilot study demonstrated that Co, Ti, Nb and Zr released from arthroplasty implants may cross the blood-CNS barriers and significantly accumulate in cerebrospinal fluid (CSF). It found merely Co levels to be significantly correlated between blood and CSF. We aimed [for full text, please go to the a.m. URL]

German Medical Science (German Research Foundation)
Universitätsmedizin Greifswald (DE), Charité - Universitätsmedizin Berlin (DE)
Openalex Percentile: Top 40%
Heavy Metal Exposure and Toxicity
DOIOpen Access PDFOpenAlex
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Metal concentrations in cerebrospinal fluid of patients with arthroplasty implants in situ – do CoCrMo components matter? · German Medical Science (German Research Foundation) (2025) | TGRS Research Map | TGRS