A non-interventional study to evaluate the safety and effectiveness of a biphasic, chondrocyte-containing biomaterial (NOVOCART ® 3D) in the treatment of localized full-thickness cartilage defects or osteochondral lesions of the knee joint (NISANIK)

Objectives and questions: The focus of this study was to evaluate the safety of NOVOCART® 3D-treatment over a period of 36 months post-transplantation. The secondary aim was to assess the enhancement of functional abilities and performance in both adult and adolescent patients undergoing treatment [for full text, please go to the a.m. URL]

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Publication Details

Journal
German Medical Science (German Research Foundation)
Published
2025-10-31
DOI
https://doi.org/10.3205/25dkou398
Primary Topic
Osteoarthritis Treatment and Mechanisms
Type
article
Field-Weighted Citation Impact
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article

A non-interventional study to evaluate the safety and effectiveness of a biphasic, chondrocyte-containing biomaterial (NOVOCART ® 3D) in the treatment of localized full-thickness cartilage defects or osteochondral lesions of the knee joint (NISANIK)

German Medical Science (German Research Foundation)
Osteoarthritis Treatment and Mechanisms
article

A non-interventional study to evaluate the safety and effectiveness of a biphasic, chondrocyte-containing biomaterial (NOVOCART ® 3D) in the treatment of localized full-thickness cartilage defects or osteochondral lesions of the knee joint (NISANIK)

article en

Abstract

Objectives and questions: The focus of this study was to evaluate the safety of NOVOCART® 3D-treatment over a period of 36 months post-transplantation. The secondary aim was to assess the enhancement of functional abilities and performance in both adult and adolescent patients undergoing treatment [for full text, please go to the a.m. URL]

German Medical Science (German Research Foundation)
OTH Regensburg (DE), Heidelberg University (DE), University Hospital Heidelberg (DE), TUM Klinikum (DE), University Hospital Regensburg (DE), Marienkrankenhaus Hamburg (DE), Klinikum Arnsberg (DE), Klinikum Sindelfingen-Böblingen (DE), Sozialstiftung Bamberg (DE), Schmerzklinik Kiel (DE), Heidelberg University (US)
Good health and well-being
Openalex Percentile: Top 34%
Osteoarthritis Treatment and Mechanisms
DOIOpen Access PDFOpenAlex
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A non-interventional study to evaluate the safety and effectiveness of a biphasic, chondrocyte-containing biomaterial (NOVOCART ® 3D) in the treatment of localized full-thickness cartilage defects or osteochondral lesions of the knee joint (NISANIK) · German Medical Science (German Research Foundation) (2025) | TGRS Research Map | TGRS