The impact of chronic stress on osteoarthritis progression in a murine model: A bidirectional relationship

Objectives and questions: Osteoarthritis (OA) is characterized by cartilage degradation and calcification, synovial inflammation, and subchondral bone sclerosis, leading to chronic pain and disabilities. The stress hormones norepinephrine (NE) and cortisol (CORT) play a role in OA pathophysiology by [for full text, please go to the a.m. URL]

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Publication Details

Journal
German Medical Science (German Research Foundation)
Published
2025-10-31
DOI
https://doi.org/10.3205/25dkou269
Primary Topic
Osteoarthritis Treatment and Mechanisms
Type
article
Field-Weighted Citation Impact
0.00
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article

The impact of chronic stress on osteoarthritis progression in a murine model: A bidirectional relationship

German Medical Science (German Research Foundation)
Osteoarthritis Treatment and Mechanisms
article

The impact of chronic stress on osteoarthritis progression in a murine model: A bidirectional relationship

article en

Abstract

Objectives and questions: Osteoarthritis (OA) is characterized by cartilage degradation and calcification, synovial inflammation, and subchondral bone sclerosis, leading to chronic pain and disabilities. The stress hormones norepinephrine (NE) and cortisol (CORT) play a role in OA pathophysiology by [for full text, please go to the a.m. URL]

German Medical Science (German Research Foundation)
Goethe University Frankfurt (DE), Christian-Albrechts-Universität zu Kiel (DE), University Hospital Schleswig-Holstein (DE), Universitätsmedizin Göttingen (DE), University Hospital Frankfurt (DE), University of Göttingen (DE), University of Lübeck (DE)
Good health and well-being
Openalex Percentile: Top 34%
Osteoarthritis Treatment and Mechanisms
DOIOpen Access PDFOpenAlex
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The impact of chronic stress on osteoarthritis progression in a murine model: A bidirectional relationship · German Medical Science (German Research Foundation) (2025) | TGRS Research Map | TGRS