Revealing the role of the YES1 gene in regulating steosarcoma occurrence and metastasis based on bioinformatics and machine learning

Objectives and questions: Osteosarcoma (OS) is a common primary malignant bone tumor in adolescents that is highly aggressive and metastatic. The YES1 gene has been shown to be associated with metastasis of various cancers, but its role in OS remains unclear. This study aimed to elucidate the mechanism [for full text, please go to the a.m. URL]

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Publication Details

Journal
German Medical Science (German Research Foundation)
Published
2025-10-31
DOI
https://doi.org/10.3205/25dkou182
Primary Topic
Hippo pathway signaling and YAP/TAZ
Type
article
Field-Weighted Citation Impact
0.00
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article

Revealing the role of the YES1 gene in regulating steosarcoma occurrence and metastasis based on bioinformatics and machine learning

German Medical Science (German Research Foundation)
Hippo pathway signaling and YAP/TAZ
article

Revealing the role of the YES1 gene in regulating steosarcoma occurrence and metastasis based on bioinformatics and machine learning

article en

Abstract

Objectives and questions: Osteosarcoma (OS) is a common primary malignant bone tumor in adolescents that is highly aggressive and metastatic. The YES1 gene has been shown to be associated with metastasis of various cancers, but its role in OS remains unclear. This study aimed to elucidate the mechanism [for full text, please go to the a.m. URL]

German Medical Science (German Research Foundation)
Jianghan University (CN), Technical University of Munich (DE)
Good health and well-being
Openalex Percentile: Top 41%
Hippo pathway signaling and YAP/TAZ
DOIOpen Access PDFOpenAlex
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Revealing the role of the YES1 gene in regulating steosarcoma occurrence and metastasis based on bioinformatics and machine learning · German Medical Science (German Research Foundation) (2025) | TGRS Research Map | TGRS