The Wnt1G177C mutation impairs fracture healing in mice

Objectives and questions: Wnt1 is essential for bone development and remodeling, with pathogenic variants linked to osteogenesis imperfecta type XV and early-onset osteoporosis. However, their impact on fracture healing remains unclear. This study investigates how the Wnt1G177C/G177C variant affects [for full text, please go to the a.m. URL]

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Publication Details

Journal
German Medical Science (German Research Foundation)
Published
2025-10-31
DOI
https://doi.org/10.3205/25dkou229
Primary Topic
Connective tissue disorders research
Type
article
Field-Weighted Citation Impact
0.00
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article

The Wnt1G177C mutation impairs fracture healing in mice

German Medical Science (German Research Foundation)
Connective tissue disorders research
article

The Wnt1G177C mutation impairs fracture healing in mice

article en

Abstract

Objectives and questions: Wnt1 is essential for bone development and remodeling, with pathogenic variants linked to osteogenesis imperfecta type XV and early-onset osteoporosis. However, their impact on fracture healing remains unclear. This study investigates how the Wnt1G177C/G177C variant affects [for full text, please go to the a.m. URL]

German Medical Science (German Research Foundation)
Universität Hamburg (DE), Universität Ulm (DE), University Medical Center Hamburg-Eppendorf (DE), Technische Hochschule Ulm (DE)
Openalex Percentile: Top 32%
Connective tissue disorders research
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