Prolonged ischemia induces oxidative stress and affects gene expression and viability of autologous cancellous bone grafts

Objectives and questions: Non-unions remain a major complication in trauma and orthopedic surgery. Autologous bone tissue still represents the gold standard in the treatment of large bone defects and non-unions. However, during revision surgery, there may be a significant delay between harvesting of [for full text, please go to the a.m. URL]