Use of transdermal patch insulin in Diabetes Mellitus: A comprehensive review

Diabetes mellitus, a widespread metabolic disorder, necessitates effective glycemic control strategies. Traditional insulin therapies, primarily via subcutaneous injections, present challenges including discomfort, poor compliance, and inconsistent absorption. Transdermal drug delivery systems (TDDS) provide an innovative, non-invasive approach to administer insulin, offering improved patient compliance and controlled release profiles. This review explores the formulation, mechanism, advantages, and limitations of insulin-loaded transdermal patches, current advancements in the field, and future prospects in transforming diabetes management.