Acute postinfectious cerebellitis in a 7-year-old child with complete resolution after intravenous immunoglobulin therapy: A case report

We report a 7-year-old child with severe gastroenteritis complicated by septic shock, later developing altered consciousness and quadriparesis. Magnetic resonance imaging (MRI) showed bilateral cerebellar hyperintensities consistent with acute postinfectious cerebellitis. Cerebrospinal fluid was normal, with no pleocytosis or viral markers, supporting an immune-mediated etiology. Intravenous immunoglobulin (IVIG) (2 g/kg over 48 h) was chosen over steroids for its immunomodulatory effect in this postinfectious context. Neurological recovery was complete. This case underscores the value of early MRI in children with new neurological deficits after infection and suggests IVIG as a safe, effective therapy for postinfectious cerebellitis when steroids pose risks.

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Publication Details

Journal
JOURNAL OF PEDIATRIC CRITICAL CARE
Published
2025-09-01
DOI
https://doi.org/10.4103/jpcc.jpcc_49_25
Primary Topic
Autoimmune Neurological Disorders and Treatments
Type
article
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article

Acute postinfectious cerebellitis in a 7-year-old child with complete resolution after intravenous immunoglobulin therapy: A case report

JOURNAL OF PEDIATRIC CRITICAL CARE
Autoimmune Neurological Disorders and Treatments
article

Acute postinfectious cerebellitis in a 7-year-old child with complete resolution after intravenous immunoglobulin therapy: A case report

article en

Abstract

We report a 7-year-old child with severe gastroenteritis complicated by septic shock, later developing altered consciousness and quadriparesis. Magnetic resonance imaging (MRI) showed bilateral cerebellar hyperintensities consistent with acute postinfectious cerebellitis. Cerebrospinal fluid was normal, with no pleocytosis or viral markers, supporting an immune-mediated etiology. Intravenous immunoglobulin (IVIG) (2 g/kg over 48 h) was chosen over steroids for its immunomodulatory effect in this postinfectious context. Neurological recovery was complete. This case underscores the value of early MRI in children with new neurological deficits after infection and suggests IVIG as a safe, effective therapy for postinfectious cerebellitis when steroids pose risks.

JOURNAL OF PEDIATRIC CRITICAL CAREVol. 12(5)
Mohammed V University (MA)
Good health and well-being
Openalex Percentile: Top 36%
Autoimmune Neurological Disorders and Treatments
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