A Study on In-Silico Supported Nephroprotective Action of Coccinia Species

There are many health problems that can be addressed using medicinal plants. The healthcare system often utilizes herbal remedies, with one particularly important plant being the Coccinia species. This plant has historically been used by various tribes as a treatment for diseases. The species has been shown to possess numerous helpful assets, counting antibacterial, analgesic, antispasmodic, antiinflammatory, antipyretic, cathartic, and expectorant properties. Chemical components such as alkaloids, glycosides, triterpenoids, phenols, flavonoids, saponins, and tannins can be found in this species. The aim of the present investigation was to isolate, purify, and identify active chemical complex from the leaves of the Coccinia grandis. The extraction process involved consuming Soxhlet apparatus to extract the leaves. Numerous phytochemical tests were conducted, and both TLC and column chromatography were used to isolate the compound. The isolated compounds were further characterized through UV, IR and analysis. The nephroprotective activity of the compound was then evaluated in an in vitro model.