Periodontal Ligament Stem Cells (PDLSC): A Promising Strategy for Periodontal Regeneration

The presage for the treatment of inflammatory periodontal disease is periodontal regeneration. The cellular therapeutic remedy is an emerging promising strategy in regenerative medicine/dentistry, particularly making use of mesenchymal-derived stem cells. MSC has the capacity to develop into adipogenic, osteogenic/odontogenic and neurogenic cells. Dental stem cells isolated from mature/immature teeth are dental pulp stem cells, stem cells from exfoliated deciduous teeth, periodontal ligament stem cells, stem cells from apical papilla and dental follicle progenitor cells. Periodontal Ligament Stem Cells (PDLSCs) are highly predictable in providing a cell source that can regenerate the lost periodontal structures. In this review, we explore the potential of PDLSCs for periodontal regeneration.