Weil's disease: A rare presentation of severe leptospirosis with multi-organ involvement

Leptospirosis is the disease caused by Leptospira interrogans, the only pathogenic species of genus Leptospira among spirochaetes. The other species of the genus Leptospira are not considered as pathogenic to humans. The spectrum of disease caused by Leptospira interrogans ranges from milder forms of the disease known as leptospirosis to severe forms known as ictero-haemorrhagic fever or Weil's disease. The involvement of multiple organs is rarely reported in leptospirosis. This is a series of three cases of severe leptospirosis with multi-organ involvement due to Leptospira interrogans from a tertiary level hospital from Uttar Pradesh, India. All the cases were having the history of contact with contaminated environment and were positive on rapid immune-chromatographic test, which was further confirmed by ELISA.