Treatment Patterns, Prognostic Factors and Survival for ALK-Positive Advanced NSCLC In Australia: Results From the Australasian Thoracic Cancers Longitudinal Cohort Study and Biobank (AURORA)

This study highlights the remarkable survival achievable in the real-world setting for some patients with ALK+ aNSCLC, compared with historical cohorts. Several clinical factors associated with survival were identified. Larger studies are needed to investigate how treatment sequences may be optimized to further improve survival outcomes.

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Publication Details

Journal
JTO Clinical and Research Reports
Published
2025-10-28
DOI
https://doi.org/10.1016/j.jtocrr.2025.100924
Primary Topic
Lung Cancer Treatments and Mutations
Type
article
Field-Weighted Citation Impact
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article

Treatment Patterns, Prognostic Factors and Survival for ALK-Positive Advanced NSCLC In Australia: Results From the Australasian Thoracic Cancers Longitudinal Cohort Study and Biobank (AURORA)

JTO Clinical and Research Reports
Lung Cancer Treatments and Mutations
article

Treatment Patterns, Prognostic Factors and Survival for ALK-Positive Advanced NSCLC In Australia: Results From the Australasian Thoracic Cancers Longitudinal Cohort Study and Biobank (AURORA)

article en

Abstract

This study highlights the remarkable survival achievable in the real-world setting for some patients with ALK+ aNSCLC, compared with historical cohorts. Several clinical factors associated with survival were identified. Larger studies are needed to investigate how treatment sequences may be optimized to further improve survival outcomes.

JTO Clinical and Research ReportsVol. 7(2)
Roche (Switzerland) (CH), The University of Melbourne (AU), Walter and Eliza Hall Institute of Medical Research (AU), Cancer Council Victoria (AU), Royal North Shore Hospital (AU), Genesis HealthCare (US), Austin Hospital (AU), Peter MacCallum Cancer Centre (AU), Fiona Stanley Hospital (AU), Sir Charles Gairdner Hospital (AU), Westmead Hospital (AU), Karolinska Institutet (SE), Chris O’Brien Lifehouse (AU), Melbourne Health (AU), The University of Adelaide (AU)
Good health and well-being
Openalex Percentile: Top 33%
Lung Cancer Treatments and Mutations
DOIOpen Access PDFOpenAlex
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Treatment Patterns, Prognostic Factors and Survival for ALK-Positive Advanced NSCLC In Australia: Results From the Australasian Thoracic Cancers Longitudinal Cohort Study and Biobank (AURORA) · JTO Clinical and Research Reports (2025) | TGRS Research Map | TGRS