Evaluation of Oxidative protection of Mimosa pudica L. against Ethanol induced gastric inflammation in Rat models

Background: Three distinct Mimosa pudica extracts were used here in study in an attempt to ascertain their anti-ulcer properties. Material and Method: Rat models with ethanol ulcers were employed for this. Therefore, pH, total acidity, ulcer index, free acidity measurement, and volume of gastric secretion estimation were the criteria used to assess anti-ulcer activity. Results: The results presented in this communication demonstrate that, wrt the standard control, the methanolic extract of Mimosa pudica leaves significantly (P < 0.01) decreased the amount of stomach acid secretion, gut pH, including the free as well total acidity values, along with ulcer index. Conclusion: The study has demonstrated the potential of the Mimosa pudica plant, in the form of a methanolic extract, as a possible therapeutic anti-ulcer agent.

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Publication Details

Journal
Research Journal of Pharmacology and Pharmacodynamics
Published
2025-10-11
DOI
https://doi.org/10.52711/2321-5836.2025.00040
Primary Topic
Lightning and Electromagnetic Phenomena
Type
article
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article

Evaluation of Oxidative protection of Mimosa pudica L. against Ethanol induced gastric inflammation in Rat models

Research Journal of Pharmacology and Pharmacodynamics
Lightning and Electromagnetic Phenomena
article

Evaluation of Oxidative protection of Mimosa pudica L. against Ethanol induced gastric inflammation in Rat models

article en

Abstract

Background: Three distinct Mimosa pudica extracts were used here in study in an attempt to ascertain their anti-ulcer properties. Material and Method: Rat models with ethanol ulcers were employed for this. Therefore, pH, total acidity, ulcer index, free acidity measurement, and volume of gastric secretion estimation were the criteria used to assess anti-ulcer activity. Results: The results presented in this communication demonstrate that, wrt the standard control, the methanolic extract of Mimosa pudica leaves significantly (P < 0.01) decreased the amount of stomach acid secretion, gut pH, including the free as well total acidity values, along with ulcer index. Conclusion: The study has demonstrated the potential of the Mimosa pudica plant, in the form of a methanolic extract, as a possible therapeutic anti-ulcer agent.

Research Journal of Pharmacology and Pharmacodynamics
Dr. C. V. Raman University (IN)
Openalex Percentile: Top 46%
Lightning and Electromagnetic Phenomena
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