Paraneoplastic cerebellar degeneration secondary to occult invasive lobular carcinoma of the breast

We report a rare case of paraneoplastic cerebellar degeneration (PCD) secondary to an occult invasive lobular breast carcinoma. The patient presented with rapidly progressive cerebellar symptoms and was found to have anti-Zic4 antibodies, an association uncommon in breast cancer. This case underscores the diagnostic challenge of PCD and highlights the importance of considering paraneoplastic causes in unexplained neurological decline. Keywords:Paraneoplastic cerebellar degeneration, breast cancer, anti-Zic4 antibodies, neurology, case report

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-10-27
DOI
https://doi.org/10.5281/zenodo.17460009
Primary Topic
Diverse Scientific and Economic Studies
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Paraneoplastic cerebellar degeneration secondary to occult invasive lobular carcinoma of the breast

Zenodo (CERN European Organization for Nuclear Research)
Diverse Scientific and Economic Studies
article

Paraneoplastic cerebellar degeneration secondary to occult invasive lobular carcinoma of the breast

article en

Abstract

We report a rare case of paraneoplastic cerebellar degeneration (PCD) secondary to an occult invasive lobular breast carcinoma. The patient presented with rapidly progressive cerebellar symptoms and was found to have anti-Zic4 antibodies, an association uncommon in breast cancer. This case underscores the diagnostic challenge of PCD and highlights the importance of considering paraneoplastic causes in unexplained neurological decline. Keywords:Paraneoplastic cerebellar degeneration, breast cancer, anti-Zic4 antibodies, neurology, case report

Zenodo (CERN European Organization for Nuclear Research)
Good health and well-being
Openalex Percentile: Top 31%
Diverse Scientific and Economic Studies
DOIOpen Access PDFOpenAlex
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Paraneoplastic cerebellar degeneration secondary to occult invasive lobular carcinoma of the breast · Zenodo (CERN European Organization for Nuclear Research) (2025) | TGRS Research Map | TGRS