48 or 370 to 1000 and More

Structure is of vital importance to structure-based drug design, significantly impacting both target selection and the rate of drug development. Increasing numbers of drug development portfolios, growing numbers of pharmaceutical and biotech companies, and demands for faster development are key drivers for technology development in macromolecular crystallography. For more than 25 years, the Industrial Macromolecular Crystallography Association Collaborative Access Team (IMCA-CAT) has focused exclusively on accelerating drug discovery and development through synchrotron-based structural biology research. Ultra- high throughput is an important goal of the facility. In pursuing this goal, the leveraging of new technologies has driven further technology development, enabling expansion and pushing limits.

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Publication Details

Journal
Structural Dynamics
Published
2025-09-01
DOI
https://doi.org/10.1063/4.0001080
Primary Topic
Enzyme Structure and Function
Type
article
Field-Weighted Citation Impact
0.00
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article

48 or 370 to 1000 and More

Structural Dynamics
Enzyme Structure and Function
article

48 or 370 to 1000 and More

article en

Abstract

Structure is of vital importance to structure-based drug design, significantly impacting both target selection and the rate of drug development. Increasing numbers of drug development portfolios, growing numbers of pharmaceutical and biotech companies, and demands for faster development are key drivers for technology development in macromolecular crystallography. For more than 25 years, the Industrial Macromolecular Crystallography Association Collaborative Access Team (IMCA-CAT) has focused exclusively on accelerating drug discovery and development through synchrotron-based structural biology research. Ultra- high throughput is an important goal of the facility. In pursuing this goal, the leveraging of new technologies has driven further technology development, enabling expansion and pushing limits.

Structural DynamicsVol. 12(5_Supplement)
Center for Advancing Health (US)
Industry, innovation and infrastructure
Openalex Percentile: Top 57%
Enzyme Structure and Function
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