Electrochemical Aptasensor for Detection of Lung Cancer Tumor Markers in Blood Plasma

The study investigates the possibility of diagnosing lung cancer through the simultaneous
\ndetection of six tumor biomarkers of this disease (CYFRA21-1, EpCAM, PLAUR, LIFR, ProGRP, and
\nCEA) in blood plasma. The levels of these proteins in blood plasma were determined using square-wave
\nvoltammetry with multiplexed electrochemical chips modified with DNA aptamers. The results obtained
\nin the study demonstrated the capability of the multiplex electrochemical aptasensor to simultaneously
\ndetect in blood plasma such traditionally used lung cancer tumor markers as CYFRA21-1, EpCAM,
\nPLAUR, LIFR, ProGRP, and CEA