Association of high-density lipoprotein profile with cardiovascular risk factors
\nin metabolic syndrome patients

Cardiovascular disease is the number one cause of death in Indonesia. The increased risk
\nof cardiovascular disease in obese patients is largely due to dyslipidemia. One of the
\nimportant lipid profiles to observe is high-density lipoprotein (HDL). One form of early
\nprevention that can be done is to predict the risk of cardiovascular disease in the future.
\nThe research wanted to determine the relationship of HDL profile with cardiovascular risk
\nfactors in patients with metabolic syndrome. The research design was cross-sectional. The
\nresearch location used in this study was around the Surabaya area starting in March-June
\n2022. The research location was carried out in Rungkut District, Surabaya, Indonesia. The
\nvariables of this study were the risk of cardiovascular disease and HDL levels. Samples of
\npatients at Siti Khodijah Throughout Hospital who met the criteria, among others: age 18-
\n60 years and willing to follow all research procedures. The sampling technique used was
\npurposive sampling. Subjects who met the criteria were then asked to fill out an informed
\nconsent. Subjects assessed the risk of cardiovascular disease with the Framingham Risk
\nScore (FRS). Test the relationship between the risk of cardiovascular disease with HDL
\nlevels with Rank Spearman. The number of respondents involved in the study was 37
\npeople. Most of the respondents have low HDL scores and high cardiovascular risk (12
\npeople). The value of the Spearman correlation coefficient was 0.897, indicating that there
\nwas a relationship between the HDL profile and cardiovascular risk of 89.7%. The
\nrelationship between HDL profile with cardiovascular risk was strong, HDL values were
\nassociated with cardiovascular risk. Therefore, a patient with metabolic syndrome should
\npay more attention to the HDL value to prevent cardiovascular-related comorbidities.