The relative Toxicity of Herbicides (Adathoda vasica, Azadirachta indica, Brugmansia versicolor, Carica papaya, Calendula officinalis) extract against larvae of Mosquito species

Abstract: The present study the larvicidal efficacy of five medicinal plant leaf extracts, Adathoda vasica, Azadirachta indica, Brugmansia versicolor, Carica papaya, and Calendula officinalis against various instar stages of the medically important mosquito Aedes aegypti. Larvae were exposed to a series of extract concentrations, and mortality rates were recorded after 24 hours. The median lethal concentration (LC₅₀/24 hours) for each plant extract was calculated using Finney’s probit analysis method. Among the tested plant extracts, Azadirachta indica exhibited the highest toxicity with the lowest LC₅₀ value of 2.3209%, followed by Carica papaya (2.4658%), Adathoda vasica (2.7907%), Calendula officinalis (5.1203%), and Brugmansia versicolor with the highest LC₅₀ value of 6.8372%. A clear dose-dependent increase in larval mortality was observed for all extracts. These findings highlight the potential of plant-based larvicides in mosquito control programs, particularly Azadirachta indica, which demonstrated the most potent larvicidal activity against Aedes aegypti larvae. Keywords: Azadiracta indica, Brugmansis versicolor, Carica papaya and Calendula officinalis etc. Title: The relative Toxicity of Herbicides (Adathoda vasica, Azadirachta indica, Brugmansia versicolor, Carica papaya, Calendula officinalis) extract against larvae of Mosquito species Author: Dr. Jipsa. J. R, Midhun. P International Journal of Novel Research in Life Sciences ISSN 2394-966X Vol. 12, Issue 5, September 2025 – October 2025 Page No: 8-17 Novelty Journals Website: www.noveltyjournals.com Published Date: 15-October-2025 DOI: https://doi.org/10.5281/zenodo.17358039 Paper Download Link (Source) https://www.noveltyjournals.com/upload/paper/The%20relative%20Toxicity%20of%20Herbicides-15102025-3.pdf