On the automated determination of p <i>K</i> <sub>a</sub> by NMR in DMSO : water mixtures

We present an automated method to determine p K a values in semi-aqueous solvents via solvent suppressed flow NMR. This technique also allows the site associated with each p K a to be ascertained.

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Publication Details

Journal
Reaction Chemistry & Engineering
Published
2025-10-22
DOI
https://doi.org/10.1039/d5re00402k
Primary Topic
Customer churn and segmentation
Type
article
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article

On the automated determination of p K a by NMR in DMSO : water mixtures

Reaction Chemistry & Engineering
Customer churn and segmentation
article

On the automated determination of p K a by NMR in DMSO : water mixtures

article en

Abstract

We present an automated method to determine p K a values in semi-aqueous solvents via solvent suppressed flow NMR. This technique also allows the site associated with each p K a to be ascertained.

Reaction Chemistry & EngineeringVol. 11(2)
AstraZeneca (Netherlands) (NL), AstraZeneca (Sweden) (SE)
Clean water and sanitation
Openalex Percentile: Top 37%
Customer churn and segmentation
DOISourceOpenAlex
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On the automated determination of p <i>K</i> <sub>a</sub> by NMR in DMSO : water mixtures · Reaction Chemistry & Engineering (2025) | TGRS Research Map | TGRS