Analysis of anticancer and antibacterial activity against bacteria resistant to aminoglycoside from the extract of Azima tetracantha L

<p>Hospital-obtained infections account for 40% of all cases, infections of the urinary tract, known as UTIs are the most common infections contracted in healthcare facilities. The current research focused on assessing the anti-bacterial properties of medicinal plants against bacteria that have developed resistance to aminoglycosides. The collected urine samples from UTI patients at various hospitals were inoculated on HiCrome Differential Agar for the isolation of pathogens. The identification of aminoglycoside-resistant bacteria was based on their cultural and morphological features. One of the methods disc diffusion was employed to analyze the antibiotic sensitivity of aminoglycoside-resistant bacteria to various commercial antibiotics, including <em>Azima tetracantha </em>L. The powdered specimens were analysed to screening of phytochemical using aqueous, acetone, and methanol extracts according to established protocols. GC-MS analysis was also performed on the <em>Azima tetracantha </em>L. plant extract, revealing various phytochemical compounds. According to previous studies, these compounds are recognized for their diverse medicinal properties. In additionally in this study we have evaluated the IC<sub>50</sub> value of the plant crude extract.</p> <p>published by the <a href="https://innspub.net/international-journal-of-biosciences/"><strong>International Journal of Biosciences | IJB</strong></a></p> <div> <div> </div> </div>

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-03-14
DOI
https://doi.org/10.12692/ijb/26
Primary Topic
Pharmacological Effects and Toxicity Studies
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Analysis of anticancer and antibacterial activity against bacteria resistant to aminoglycoside from the extract of Azima tetracantha L

Zenodo (CERN European Organization for Nuclear Research)
Pharmacological Effects and Toxicity Studies
article

Analysis of anticancer and antibacterial activity against bacteria resistant to aminoglycoside from the extract of Azima tetracantha L

article en

Abstract

<p>Hospital-obtained infections account for 40% of all cases, infections of the urinary tract, known as UTIs are the most common infections contracted in healthcare facilities. The current research focused on assessing the anti-bacterial properties of medicinal plants against bacteria that have developed resistance to aminoglycosides. The collected urine samples from UTI patients at various hospitals were inoculated on HiCrome Differential Agar for the isolation of pathogens. The identification of aminoglycoside-resistant bacteria was based on their cultural and morphological features. One of the methods disc diffusion was employed to analyze the antibiotic sensitivity of aminoglycoside-resistant bacteria to various commercial antibiotics, including <em>Azima tetracantha </em>L. The powdered specimens were analysed to screening of phytochemical using aqueous, acetone, and methanol extracts according to established protocols. GC-MS analysis was also performed on the <em>Azima tetracantha </em>L. plant extract, revealing various phytochemical compounds. According to previous studies, these compounds are recognized for their diverse medicinal properties. In additionally in this study we have evaluated the IC<sub>50</sub> value of the plant crude extract.</p> <p>published by the <a href="https://innspub.net/international-journal-of-biosciences/"><strong>International Journal of Biosciences | IJB</strong></a></p> <div> <div> </div> </div>

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 27%
Pharmacological Effects and Toxicity Studies
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.