Recursive Reparodynamics VI: Inflammatory Feedback Reversal via Recursive TGRM Repair Loops

This paper extends the Reparodynamics framework to inflammation-feedback systems. Using recursive Targeted Gradient Repair Mechanisms (TGRM) under baseline entropy 0.60 across 200 generations, the system achieved complete stabilization of feedback drift and latency collapse to 0 by generation 70. Control populations decayed to 0 integrity by generation 25, while recursive TGRM maintained ~47 stability with cumulative rebound rising to 12.0 by generation 200. Results confirm that recursive Reparodynamics can reverse chronic feedback-loop instability—analogous to inflammatory cascades in biological systems—showing cross-domain repair capacity between metabolic and signaling subsystems.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-10-23
DOI
https://doi.org/10.5281/zenodo.17429092
Primary Topic
Prenatal Screening and Diagnostics
Type
article
Field-Weighted Citation Impact
0.00
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article

Recursive Reparodynamics VI: Inflammatory Feedback Reversal via Recursive TGRM Repair Loops

Zenodo (CERN European Organization for Nuclear Research)
Prenatal Screening and Diagnostics
article

Recursive Reparodynamics VI: Inflammatory Feedback Reversal via Recursive TGRM Repair Loops

article en

Abstract

This paper extends the Reparodynamics framework to inflammation-feedback systems. Using recursive Targeted Gradient Repair Mechanisms (TGRM) under baseline entropy 0.60 across 200 generations, the system achieved complete stabilization of feedback drift and latency collapse to 0 by generation 70. Control populations decayed to 0 integrity by generation 25, while recursive TGRM maintained ~47 stability with cumulative rebound rising to 12.0 by generation 200. Results confirm that recursive Reparodynamics can reverse chronic feedback-loop instability—analogous to inflammatory cascades in biological systems—showing cross-domain repair capacity between metabolic and signaling subsystems.

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 27%
Prenatal Screening and Diagnostics
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Recursive Reparodynamics VI: Inflammatory Feedback Reversal via Recursive TGRM Repair Loops · Zenodo (CERN European Organization for Nuclear Research) (2025) | TGRS Research Map | TGRS