THERAPEUTIC POTENTIAL OF BRASSICA OLERACEA EXTRACTS ON LEUKEMIA: AN IN VITRO ANALYSIS

Cold water hot water and ethanol extracts from Brassica oleracea plant they were prepared and tested for their antioxidant activity and efficacy against leukemia cells. All of the extracts showed significant antioxidant activity. All the extracts could kill the majority (50-75%) of abnormal cell among primary cells harvested from 3 patients with acute lympho-blastic leukemia (ALL) and 3 with acute myeloid leukemia (AML). DNA fragmentation patterns were detected within treated cells and inferred targeted cell death by apoptosis.The metabolites within the ext-racts may act as tumor inhibitors that promote apoptosis. In addition the plant extracts may be used to supplement or replace established drugs treatments .