Recursive Reparodynamics in DNA Damage Repair: Entropy Rebound and Mutation Stability

This study presents the third recursive Reparodynamics simulation validating the Targeted Gradient Repair Mechanism (TGRM) at the genomic level. The experiment modeled DNA damage recovery under baseline entropy 0.3 across 100 generations. Results show complete repair efficiency (1.00) by generation 30 and long-term stability at ≈ 66.41 integrity, with a cumulative entropy rebound of 6.15. These outcomes demonstrate mutation-level stabilization through recursive adaptive repair, extending Reparodynamics from metabolic rejuvenation to genetic persistence.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-10-23
DOI
https://doi.org/10.5281/zenodo.17428167
Primary Topic
DNA Repair Mechanisms
Type
article
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article

Recursive Reparodynamics in DNA Damage Repair: Entropy Rebound and Mutation Stability

Zenodo (CERN European Organization for Nuclear Research)
DNA Repair Mechanisms
article

Recursive Reparodynamics in DNA Damage Repair: Entropy Rebound and Mutation Stability

article en

Abstract

This study presents the third recursive Reparodynamics simulation validating the Targeted Gradient Repair Mechanism (TGRM) at the genomic level. The experiment modeled DNA damage recovery under baseline entropy 0.3 across 100 generations. Results show complete repair efficiency (1.00) by generation 30 and long-term stability at ≈ 66.41 integrity, with a cumulative entropy rebound of 6.15. These outcomes demonstrate mutation-level stabilization through recursive adaptive repair, extending Reparodynamics from metabolic rejuvenation to genetic persistence.

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 44%
DNA Repair Mechanisms
DOIOpen Access PDFOpenAlex
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Recursive Reparodynamics in DNA Damage Repair: Entropy Rebound and Mutation Stability · Zenodo (CERN European Organization for Nuclear Research) (2025) | TGRS Research Map | TGRS