When Supplements Turn Dangerous: Glucocorticoid-Induced Adrenal Insufficiency From Hidden Steroids

We report a case of glucocorticoid-induced adrenal insufficiency following the use of 3 different herbal supplements containing hidden steroids. The patient presented with nonspecific symptoms, including fatigue and gastrointestinal upset, complicating diagnosis. These supplements contributed to life-threatening infections and hemorrhagic shock from an upper gastrointestinal bleed. This case emphasizes the clinical challenges and health risks associated with the use of unregulated supplements. Many patients consider these supplements safe; however, they may contain ingredients that pose serious health threats. Increased awareness, comprehensive history, and careful diagnostic approaches are crucial in effectively managing such cases.