Aortic Thrombosis Occurring in a Patient with Behçet Disease and Multiple Thrombophilias: A Case Report

Abstract Behçet disease represents an inflammatory condition capable of affecting blood vessels in both venous and arterial circulations, a clinical pattern like the one encountered in antiphospholipid syndrome, although disease mechanisms differ. This case report presents the occurrence of an acute episode of paraparesis due to aortic thrombosis in a patient with a known history of Behçet disease, treated by way of a thromboembolectomy. There were no systemic inflammatory syndrome or other suggestive symptoms for a relapse of the patient’s underlying condition. A hypercoagulable workup revealed the presence of several prothrombotic factors, including antithrombin III and protein S deficiencies, alongside the confirmation of a positive lupus anticoagulant. This case highlights the clinical challenge that the aortic thrombosis posed, which was finally attributed to the particular association of prothrombotic factors, in a patient with an apparently inactive Behçet disease and an antiphospholipid syndrome that had probably played the most significant role in the acute presentation.