An HIV-Infected Patient Developed Immune Reconstitution Inflammatory Syndrome Immune Reconstitution Inflammatory Syndrome After Antiretroviral Therapy and Was Diagnosed with Primary Immune Thrombocytopenia, Latent Autoimmune Diabetes in Adults, and H

Lele Yu,1 Binhai Zhang,1 Hu Wan,1 Huimin Ying,2 Xiaolu Qian2 1Department II of Infectious Diseases, Hangzhou Xixi Hospital, Hangzhou Sixth People’s Hospital, Hangzhou, Zhejiang, 310023, People’s Republic of China; 2Department of Endocrinology, Hangzhou Xixi Hospital, Hangzhou Sixth People’s Hospital, Hangzhou, Zhejiang, 310023, People’s Republic of ChinaCorrespondence: Xiaolu Qian, Email [email protected]: Immune reconstitution inflammatory syndrome (IRIS) is closely associated with antiretroviral therapy (ART) and poses a clinical challenge in HIV management.Case Presentation: This report describes an HIV-infected individual who developed Primary immune thrombocytopenia, latent autoimmune diabetes in adults, and Hashimoto thyroiditis after starting ART.Conclusion: Antiretroviral therapy (ART) may result in thrombocytopenia, fluctuations in blood glucose levels, thyroid dysfunction, diabetic ketoacidosis (DKA), or thyroid crisis. Healthcare professionals should evaluate the potential links between immune reconstitution inflammatory syndrome (IRIS) and latent autoimmune diabetes in adults (LADA), immune thrombocytopenia (ITP), as well as Hashimoto thyroiditis (HT).Keywords: HIV, IRIS, LADA, case report