Spirulina-Based Herbal Oral Rinse: A Natural Approach to Mucosal Wound Healing

This project focuses on the development of a Spirulina-based herbal oral rinse formulated to promote the healing of oral mucosal wounds, including ulcers, traumatic lesions, post-dental surgery injuries, and chemotherapy-induced mucositis. The oral rinse utilizes Spirulina (Arthrospira platensis), a nutrient-rich microalga known for its antioxidant, anti-inflammatory, and tissue-regenerative properties, as the primary active ingredient. To enhance its therapeutic potential, the first formulation incorporates herbal extracts such as Amla juice, Clove, Hibiscus and the second formulation incorporates herbal extracts such as Amla juice, Tulsi, Charcoal, all well-documented for their antibacterial, soothing, and healing capabilities. The resulting rinse is pH-balanced, and biocompatible, making it safe for regular use even in patients with sensitive oral tissues. In vitro evaluations have demonstrated the formulation’s ability to significantly reduce microbial load, alleviate inflammation, and accelerate epithelial regeneration. The plant-based bioactive offers a natural, non-toxic alternative to chemical-based mouthwashes, making it a promising solution for effective oral hygiene management and wound care. Its application can be extended to dental clinics, cancer care, and general oral health maintenance, supporting a shift toward green, sustainable therapeutics in biomedical care.