Electrolyte Imbalance Associated with Antibiotic Therapy: A Case Report on Piperacillin–Tazobactam Induced Hypokalemia

The patient was a 56-year-old woman with a history of type 2 diabetes mellitus (T2DM) who had a one-month-old right foot ulcer that was accompanied by swelling, pus discharge, and an unpleasant feeling. Clinical evaluation revealed secondary bacterial involvement in a diabetic foot infection. Broad-spectrum intravenous antibiotics (PiperacillinTazobactam and Clindamycin), analgesics, and stomach protection were all part of the first treatment. Amputation of the right foot was necessary because of the severity of the illness and worries about sepsis. Antibiotic treatment was continued after surgery, along with supportive care and pain control. Reduced antibiotic dosage, nephroprotective medications (taurine + acetylcysteine, sodium bicarbonate), insulin therapy, and blood transfusions were necessary changes in treatment due to decreasing renal function and anemia. long-term care with an emphasis on antiplatelet medication (clopidogrel, aspirin) and rigorous glucose control using insulin and Glipizide. Renal function monitoring and a diabetic diet were stressed for the best possible recovery. The example emphasizes how important it is to treat diabetic foot infections with glycemic control, early intervention, and multidisciplinary care in order to avoid serious sequelae.