Antitumor Effect of 5-Aminolevulinic Acid Methyl Ester-Mediated Photodynamic Therapy on Local Skin Melanoma and Its Metastasized Tumor, in Relation with Antitumor Immunity

ALA-Me-PDT had significant inhibitory effects both on local tumor growth and distant lung metastasis of melanoma. There was also significant antitumor immunity caused by ALA-Me-PDT. Results of the present study provide a potential possibility for ALA-Me-PDT in the treatment of skin melanoma and its metastasis.

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Publication Details

Journal
Journal of Environmental Pathology Toxicology and Oncology
Published
2025-10-14
DOI
https://doi.org/10.1615/jenvironpatholtoxicoloncol.2025058961
Primary Topic
Photodynamic Therapy Research Studies
Type
article
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article

Antitumor Effect of 5-Aminolevulinic Acid Methyl Ester-Mediated Photodynamic Therapy on Local Skin Melanoma and Its Metastasized Tumor, in Relation with Antitumor Immunity

Journal of Environmental Pathology Toxicology and Oncology
Photodynamic Therapy Research Studies
article

Antitumor Effect of 5-Aminolevulinic Acid Methyl Ester-Mediated Photodynamic Therapy on Local Skin Melanoma and Its Metastasized Tumor, in Relation with Antitumor Immunity

article en

Abstract

ALA-Me-PDT had significant inhibitory effects both on local tumor growth and distant lung metastasis of melanoma. There was also significant antitumor immunity caused by ALA-Me-PDT. Results of the present study provide a potential possibility for ALA-Me-PDT in the treatment of skin melanoma and its metastasis.

Journal of Environmental Pathology Toxicology and OncologyVol. 45(1)
Tibet University (CN), University of Kinshasa (CD), Wuhan University (CN), Zhongnan Hospital of Wuhan University (CN)
Good health and well-being
Openalex Percentile: Top 34%
Photodynamic Therapy Research Studies
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