Efficacy and Safety of Sodium-Glucose Cotransporter-2 Inhibitors in Patients With Refractory Cirrhotic Ascites and Diabetes: Scoping Review Protocol

By systematically identifying and summarizing original studies that assess the efficacy of SGLT2i in this unique patient population, the review will provide insight into the therapeutic potential of this drug class beyond glycemic control. It will also highlight the strengths and limitations of the existing literature, identify key knowledge gaps, and suggest directions for future research. Ultimately, this review may support the rationale for further clinical investigation and the development of targeted therapies for a high-risk group of patients with limited treatment options.

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Publication Details

Journal
JMIR Research Protocols
Published
2025-10-15
DOI
https://doi.org/10.2196/77587
Primary Topic
Oceanographic and Atmospheric Processes
Type
article
Field-Weighted Citation Impact
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article

Efficacy and Safety of Sodium-Glucose Cotransporter-2 Inhibitors in Patients With Refractory Cirrhotic Ascites and Diabetes: Scoping Review Protocol

JMIR Research Protocols
Oceanographic and Atmospheric Processes
article

Efficacy and Safety of Sodium-Glucose Cotransporter-2 Inhibitors in Patients With Refractory Cirrhotic Ascites and Diabetes: Scoping Review Protocol

article en

Abstract

By systematically identifying and summarizing original studies that assess the efficacy of SGLT2i in this unique patient population, the review will provide insight into the therapeutic potential of this drug class beyond glycemic control. It will also highlight the strengths and limitations of the existing literature, identify key knowledge gaps, and suggest directions for future research. Ultimately, this review may support the rationale for further clinical investigation and the development of targeted therapies for a high-risk group of patients with limited treatment options.

JMIR Research ProtocolsVol. 15
University of Nevada, Las Vegas (US), Dow University of Health Sciences (PK), Mass General Brigham (US)
Good health and well-being
Openalex Percentile: Top 38%
Oceanographic and Atmospheric Processes
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