Formulation Of Effervescent Granules of Ashwagandha and Okra: For Gut and Stress Relief

Effervescent granules have gained importance as an innovative oral dosage form because of their ability to enhance patient compliance, improve palatability, and increase the bioavailability of active constituents. The present work focused on the development and evaluation of effervescent granules containing Withania somnifera (Ashwagandha) and Abelmoschus esculentus (Okra) to provide combined therapeutic benefits for stress relief and gastrointestinal wellness. Ashwagandha is well documented for its adaptogenic, anxiolytic, and cortisol-modulating effects, making it valuable in stress management. Okra, on the other hand, is rich in mucilage and dietary fiber, which play a vital role in promoting gut health and supporting digestive processes. By combining these two herbal actives, the formulation aims to deliver a dual therapeutic effect that addresses both mental and digestive well-being. The granules were prepared using sodium bicarbonate and citric acid as effervescent agents, while natural sweeteners and flavors were incorporated to improve taste and acceptability. The prepared formulation was evaluated for parameters such as effervescence time, dissolution profile, stability, and moisture content to ensure quality and effectiveness. This approach highlights the potential of effervescent granules as a patient-friendly, multifunctional dosage form. The combination of Ashwagandha and Okra not only offers improved therapeutic efficacy but also enhances compliance through a palatable and convenient delivery system.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-10-13
DOI
https://doi.org/10.5281/zenodo.17339890
Primary Topic
Phytochemicals and Medicinal Plants
Type
article
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article

Formulation Of Effervescent Granules of Ashwagandha and Okra: For Gut and Stress Relief

Zenodo (CERN European Organization for Nuclear Research)
Phytochemicals and Medicinal Plants
article

Formulation Of Effervescent Granules of Ashwagandha and Okra: For Gut and Stress Relief

article en

Abstract

Effervescent granules have gained importance as an innovative oral dosage form because of their ability to enhance patient compliance, improve palatability, and increase the bioavailability of active constituents. The present work focused on the development and evaluation of effervescent granules containing Withania somnifera (Ashwagandha) and Abelmoschus esculentus (Okra) to provide combined therapeutic benefits for stress relief and gastrointestinal wellness. Ashwagandha is well documented for its adaptogenic, anxiolytic, and cortisol-modulating effects, making it valuable in stress management. Okra, on the other hand, is rich in mucilage and dietary fiber, which play a vital role in promoting gut health and supporting digestive processes. By combining these two herbal actives, the formulation aims to deliver a dual therapeutic effect that addresses both mental and digestive well-being. The granules were prepared using sodium bicarbonate and citric acid as effervescent agents, while natural sweeteners and flavors were incorporated to improve taste and acceptability. The prepared formulation was evaluated for parameters such as effervescence time, dissolution profile, stability, and moisture content to ensure quality and effectiveness. This approach highlights the potential of effervescent granules as a patient-friendly, multifunctional dosage form. The combination of Ashwagandha and Okra not only offers improved therapeutic efficacy but also enhances compliance through a palatable and convenient delivery system.

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 33%
Phytochemicals and Medicinal Plants
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