Heterocyclic Scaffold of Interest: Pyrimido [2, 3-b] Benzothiazole as Emerging Multifunctional Bioactive Agents

Pyrimido [2, 3-b]benzothiazole derivatives have emerged as a prominent pharmacophore with pharmacological activities viz. antibacterial, antifungal, antiviral, antitubercular, anti-inflammatory, antioxidant, sedative, muscle relaxant, anti-allergic, and anticancer properties. Many drugs containing benzothiazole, such as Zopolrestat, Riluzole, Frentizole, Ethoxzolamine, Dimazole, and Flutemetamol, etc are available for the treatment of a wide range of diseases in human beings. The pyrimidine (1, 3-diazine) is also are important compound possessing various activities. The review article on the heterocyclic scaffold of interest: pyrimido [2, 3-b]benzothiazole as emerging multifunctional bioactive agents contains the therapeutic potential of benzothiazole fused with pyrimidine.