Analgesic Effects of Acupuncture Compared to Tramadol and Meloxicam in Cats Undergoing Ovariohysterectomy

Background: Acupuncture has analgesic effects in animals. Common analgesics, such as opioids and anti-inflammatory drugs, are widely used to control postoperative pain in cats, but they can cause serious side effects. On the other hand, acupuncture can play a crucial role in replacing this kind of drug. Objectives: This study aims to evaluate the analgesic effects of acupuncture compared to tramadol and meloxicam on postoperative pain in cats after ovariohysterectomy. Methods: Forty-five adult stray cats were randomly distributed into three groups of fifteen animals each: TR: Tramadol (2 mg/kg IV) administered before anesthesia induction; ML: Meloxicam (0.2 mg/kg SC) administered after placement of the last skin suture; AC: Bilateral acupoints from kidney 11 (KI-11) to kidney 17 (KI-17) were stimulated. Postoperative pain was evaluated using the revised Glasgow composite pain scale-Feline and UNESP-Botucatu multidimensional composite pain scale (MCPS) up to 24 h after surgery. Rescue analgesia was provided intramuscularly with tramadol (2 mg/kg). Data were analyzed using the Kruskal-Wallis, Fisher’s exact probability test, and Friedman test. P<0.05 is considered significant. Results: Mean pain scores did not significantly differ among groups at any time point (P>0.05). The pain score and prevalence of rescue analgesia did not differ from the treatment groups over 24 h. Conclusion: Based on this study, analgesic effects of acupuncture were like tramadol and meloxicam during the first 24 h after Ovariohysterectomy in cats.

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Publication Details

Journal
Iranian Journal of Veterinary Medicine
Published
2025-10-13
DOI
https://doi.org/10.32598/ijvm.20.1.1005447
Primary Topic
Veterinary Pharmacology and Anesthesia
Type
article
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article

Analgesic Effects of Acupuncture Compared to Tramadol and Meloxicam in Cats Undergoing Ovariohysterectomy

Iranian Journal of Veterinary Medicine
Veterinary Pharmacology and Anesthesia
article

Analgesic Effects of Acupuncture Compared to Tramadol and Meloxicam in Cats Undergoing Ovariohysterectomy

article en

Abstract

Background: Acupuncture has analgesic effects in animals. Common analgesics, such as opioids and anti-inflammatory drugs, are widely used to control postoperative pain in cats, but they can cause serious side effects. On the other hand, acupuncture can play a crucial role in replacing this kind of drug. Objectives: This study aims to evaluate the analgesic effects of acupuncture compared to tramadol and meloxicam on postoperative pain in cats after ovariohysterectomy. Methods: Forty-five adult stray cats were randomly distributed into three groups of fifteen animals each: TR: Tramadol (2 mg/kg IV) administered before anesthesia induction; ML: Meloxicam (0.2 mg/kg SC) administered after placement of the last skin suture; AC: Bilateral acupoints from kidney 11 (KI-11) to kidney 17 (KI-17) were stimulated. Postoperative pain was evaluated using the revised Glasgow composite pain scale-Feline and UNESP-Botucatu multidimensional composite pain scale (MCPS) up to 24 h after surgery. Rescue analgesia was provided intramuscularly with tramadol (2 mg/kg). Data were analyzed using the Kruskal-Wallis, Fisher’s exact probability test, and Friedman test. P<0.05 is considered significant. Results: Mean pain scores did not significantly differ among groups at any time point (P>0.05). The pain score and prevalence of rescue analgesia did not differ from the treatment groups over 24 h. Conclusion: Based on this study, analgesic effects of acupuncture were like tramadol and meloxicam during the first 24 h after Ovariohysterectomy in cats.

Iranian Journal of Veterinary MedicineVol. 20(1)
University of Tehran (IR), Tehran University of Medical Sciences (IR)
Good health and well-being
Openalex Percentile: Top 37%
Veterinary Pharmacology and Anesthesia
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