Cover Feature: Inhibition of Lysosomal Cathepsin A and Neuraminidase 1 Interaction by Anti‐Obesity Cyclic Peptide (Chem. Eur. J. 56/2024)

The Cover Feature highlights the docking model of lysosomal protective protein cathepsin A (PPCA) and the synthetic derivative of stylissatin A (SA), a cyclic heptapeptide from the Papua New Guinean marine sponge Stylissa sp. Focusing on this new-found protein–protein interaction inhibition mechanism of SA could lead to the development of new anti-obesity drugs. More information can be found in the Research Article by M. Kita and co-workers (DOI: 10.1002/chem.202402049).