A Review of Anti-Fungal Cream

This study aimed to develop a cream utilizing natural ingredients for treating fungal skin infections and improving overall skin health. The formulation represents an herbal medicinal cream containing antifungal agents, providing a systematic approach to managing cutaneous fungal infections. Topical application remains the preferred delivery method for such conditions. Creating a localized drug delivery system with systemic potential offers significant advantages over conventional administration routes. The cream incorporates botanical components recognized for their antifungal efficacy, including Aloe vera, Neem, Tulsi, and Pot Marigold (calendula) oil. The base formulation consists of beeswax, liquid paraffin, borax, and methyl paraben, with rose oil added for fragrance. The combination of these extracted natural ingredients produces a potent antifungal effect. The formulated herbal antifungal cream underwent rigorous evaluation for both efficacy and safety. Comprehensive assessments were conducted on various physicochemical parameters: physical appearance (color, odor, texture, state), pH, spreadability, homogeneity, removability, after-feel, smear type, irritancy, and antifungal activity. The final medicated cream demonstrated optimal viscosity and color, complemented by a functional rose water aroma. The global prevalence of fungal infections is rising, currently affecting 20-25% of the population and contributing to 30-50% of worldwide mortality. Contributing factors include low socioeconomic status, overcrowding, poor sanitation, and nutritional deficiencies. Trophic conditions further promote the proliferation of fungal diseases. For centuries, medicinal herbs have served as crucial resources in both traditional and contemporary medicine for managing infectious and non-infectious dermatological conditions. These plants contain active phyto constituents like polyphenols and antioxidants, which minimize adverse reactions and support the body's natural detoxification mechanisms. Antifungal creams effectively reduce inflammation, prevent wrinkles and acne, enhance blood circulation and cellular metabolism, and are suitable for sensitive, dry, and delicate skin types. Common ingredients in antifungal formulations include Asafoetida, Liquorice, Neem, Karanji oil, Alcohol, Stearic acid, Water, Bees wax, and Methyl paraben