Ebola Virus Disease in sub-Saharan Africa: History,Contemporary Epidemiology and Recommendations

Between 2017 and 7 March 2025, Ebola virus disease occasioned eight outbreakskilling 2,471 people out of 3,892 cases in sub-Saharan Africa. Given the pandemic capacities ofthe largest Ebola epidemics that occurred in West Africa from 2014-2016 and the socio-economic catastrophe wrought by the COVID-19 pandemic, all hands must be on deck tomitigate recurrent Ebola outbreaks. Hence, this piece explores the historical trajectory of Ebolavirus disease and its epidemiological attributes in the contemporary era. We deployed a narrativereview of relevant articles on the Ebola virus disease from its inception in 1976 to 2025. Between2001 and 2025, 26 outbreaks of EVD occurred in sub-Saharan Africa, with an average casefatality rate of 43 percent. We discovered that 46 percent of the epidemics occurred in the DRCongo, and Zaire Ebola strains were responsible for 73 percent of outbreaks