Enhanced Nanopore Sequencing Analysis via Hyperdimensional Embedding and Recursive Causal Inference (HENCRI)
**Abstract:** This paper introduces Hyperdimensional Embedding and Recursive Causal Inference (HENCRI), a novel framework for significantly improving accuracy and throughput in nanopore sequencing data analysis. Leveraging hyperdimensional vector spaces for nucleotide representation and a recursive causal inference engine for signal denoising and error correction, HENCRI achieves a 1.5x improvement in base calling accuracy and a 2.0x speedup in processing time compared to state-of-the-art methods. The system's self-optimizing architecture incorporates a human-AI feedback loop for continual improvement, demonstrating immediate commercial viability and paving the way for scalable, real-time genome sequencing.
Institutions
- Freed–Hardeman University (US)
Publication Details
- Journal
- Zenodo (CERN European Organization for Nuclear Research)
- Published
- 2025-10-11
- DOI
- https://doi.org/10.5281/zenodo.17329434
- Primary Topic
- Nanopore and Nanochannel Transport Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00