A System and Method for Geometrodynamic Neuromodulation via a Constellated Emitter Platform

Background of the Invention The treatment of neurological and psychiatric disorders has historically relied upon two primary paradigms: pharmacological intervention and direct neuromodulation. While these approaches have provided benefits to many, they are circumscribed by fundamental limitations rooted in their conceptualization of the brain and mind. Pharmacological interventions, such as selective serotonin reuptake inhibitors (SSRIs), operate by modulating neurochemical balances within the brain. This approach treats the mind as a chemical system, aiming to correct putative imbalances. However, this method often only manages symptoms without addressing the underlying structural or dynamic etiology of a disorder. Consequently, a significant portion of the patient population, particularly those with Treatment-Resistant Depression (TRD) or refractory anxiety disorders, fails to respond adequately to such treatments.1 Furthermore, systemic administration often leads to undesirable side effects and precludes a truly personalized therapeutic regimen.1 Existing neuromodulation techniques, including Transcranial Magnetic Stimulation (TMS) and invasive Deep Brain Stimulation (DBS), represent an advance by targeting specific physical regions of the brain.2 These methods treat the brain as an electrochemical machine composed of discrete, functionally localized parts. Stimulation is applied to a specific anatomical coordinate to excite or inhibit neural activity. However, this approach remains fundamentally limited. It fails to address the holistic, distributed, and dynamic nature of a mental state, which emerges from the complex interplay of numerous brain networks rather than the activity of a single locus.1 These modalities are often confined to a clinical setting, require repeated sessions, and, in the case of DBS, involve significant surgical risk.1 The prior art, therefore, is characterized by a persistent "semantic gap" (anlamsal boşluk) between objective, measurable brain data (e.g., neural firing, blood-oxygen levels) and the subjective, first-person experience of a cognitive or emotional state.1 Current therapeutic modalities are unable to bridge this gap, as they lack a method to directly interface with and modulate the holistic, dynamic, and geometric structure of a subject's subjective reality itself. There exists a need for a therapeutic system that transcends the treatment of the brain's constituent parts and instead addresses the emergent, organizational principles of the mind. The present invention addresses this fundamental deficiency by providing a system and method for diagnosing and treating the geometry of a subject's cognitive state-space, thereby introducing a new paradigm of "geometric psychiatry".1

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-10-11
DOI
https://doi.org/10.5281/zenodo.17317964
Primary Topic
Neurological disorders and treatments
Type
article
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article

A System and Method for Geometrodynamic Neuromodulation via a Constellated Emitter Platform

Zenodo (CERN European Organization for Nuclear Research)
Neurological disorders and treatments
article

A System and Method for Geometrodynamic Neuromodulation via a Constellated Emitter Platform

article en

Abstract

Background of the Invention The treatment of neurological and psychiatric disorders has historically relied upon two primary paradigms: pharmacological intervention and direct neuromodulation. While these approaches have provided benefits to many, they are circumscribed by fundamental limitations rooted in their conceptualization of the brain and mind. Pharmacological interventions, such as selective serotonin reuptake inhibitors (SSRIs), operate by modulating neurochemical balances within the brain. This approach treats the mind as a chemical system, aiming to correct putative imbalances. However, this method often only manages symptoms without addressing the underlying structural or dynamic etiology of a disorder. Consequently, a significant portion of the patient population, particularly those with Treatment-Resistant Depression (TRD) or refractory anxiety disorders, fails to respond adequately to such treatments.1 Furthermore, systemic administration often leads to undesirable side effects and precludes a truly personalized therapeutic regimen.1 Existing neuromodulation techniques, including Transcranial Magnetic Stimulation (TMS) and invasive Deep Brain Stimulation (DBS), represent an advance by targeting specific physical regions of the brain.2 These methods treat the brain as an electrochemical machine composed of discrete, functionally localized parts. Stimulation is applied to a specific anatomical coordinate to excite or inhibit neural activity. However, this approach remains fundamentally limited. It fails to address the holistic, distributed, and dynamic nature of a mental state, which emerges from the complex interplay of numerous brain networks rather than the activity of a single locus.1 These modalities are often confined to a clinical setting, require repeated sessions, and, in the case of DBS, involve significant surgical risk.1 The prior art, therefore, is characterized by a persistent "semantic gap" (anlamsal boşluk) between objective, measurable brain data (e.g., neural firing, blood-oxygen levels) and the subjective, first-person experience of a cognitive or emotional state.1 Current therapeutic modalities are unable to bridge this gap, as they lack a method to directly interface with and modulate the holistic, dynamic, and geometric structure of a subject's subjective reality itself. There exists a need for a therapeutic system that transcends the treatment of the brain's constituent parts and instead addresses the emergent, organizational principles of the mind. The present invention addresses this fundamental deficiency by providing a system and method for diagnosing and treating the geometry of a subject's cognitive state-space, thereby introducing a new paradigm of "geometric psychiatry".1

Zenodo (CERN European Organization for Nuclear Research)
Istanbul Medipol University (TR)
Good health and well-being
Openalex Percentile: Top 37%
Neurological disorders and treatments
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